Presentation Type

Poster

Full Name of Faculty Mentor

Daniel Williams, Biology

Major

Biology

Presentation Abstract

Phages are viruses that infect specific bacterial cells in order to reproduce. Many of these phages can infect and kill medically relevant bacterial species. As part of SEA-PHAGES, Coastal students have discovered two phages, Phayeta and Greco Etereo, that infect Mycobacterium smegmatis, which is closely related to the causative agent of tuberculosis. For our purposes we are annotating the phages Phayeta and Greco Etereo and comparing them to other previously annotated phages to help determine the function of the genes they contain. By doing this comparative analysis, we are increasing the understanding of phage biology and the roles of individual genes, while observing genome evolution in action. Expanding the knowledge of phage biology is critical for understanding unique biological mechanisms and how they can be medically utilized. Additionally, we may be able to discover the use of specific phages in their employment in therapeutic methods.

Start Date

12-4-2023 4:00 PM

End Date

12-4-2023 6:00 PM

Disciplines

Biology

Included in

Biology Commons

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Apr 12th, 4:00 PM Apr 12th, 6:00 PM

Genome Annotation of phages Phayeta and Greco Etereo

Phages are viruses that infect specific bacterial cells in order to reproduce. Many of these phages can infect and kill medically relevant bacterial species. As part of SEA-PHAGES, Coastal students have discovered two phages, Phayeta and Greco Etereo, that infect Mycobacterium smegmatis, which is closely related to the causative agent of tuberculosis. For our purposes we are annotating the phages Phayeta and Greco Etereo and comparing them to other previously annotated phages to help determine the function of the genes they contain. By doing this comparative analysis, we are increasing the understanding of phage biology and the roles of individual genes, while observing genome evolution in action. Expanding the knowledge of phage biology is critical for understanding unique biological mechanisms and how they can be medically utilized. Additionally, we may be able to discover the use of specific phages in their employment in therapeutic methods.

 

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