Presentation Type

Poster

Full Name of Faculty Mentor

Megan Cevasco, Biology

Major

Biology

Presentation Abstract

The Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Sciences (SEA-PHAGES) program was formed to conduct research on bacteriophages, viruses that infect bacteria. Using the bacterial host Mycobacterium smegmatis, DuncansLeg was isolated from a soil sample found on August 27th, 2021, at Coastal Carolina University's Campus. The enriched isolate obtained from an environmental distillate was purified via picking a well-isolated plaque and amplified by making webbed plates in preparation for DNA extraction. This isolate's DNA was characterized and analyzed through restriction digests. Once we obtained enough lysate we were able to send in the samples to be sequenced and further reviewed by bioinformatic analyses. DuncansLeg is a temperate phage that is a part of the L3 subcluster with 75,593 base pairs.

Location

Poster Session 2

Start Date

13-4-2022 4:30 PM

End Date

13-4-2022 6:30 PM

Disciplines

Biology

Included in

Biology Commons

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Apr 13th, 4:30 PM Apr 13th, 6:30 PM

Discovery and Investigation of Novel Bacteriophage DuncansLeg

Poster Session 2

The Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Sciences (SEA-PHAGES) program was formed to conduct research on bacteriophages, viruses that infect bacteria. Using the bacterial host Mycobacterium smegmatis, DuncansLeg was isolated from a soil sample found on August 27th, 2021, at Coastal Carolina University's Campus. The enriched isolate obtained from an environmental distillate was purified via picking a well-isolated plaque and amplified by making webbed plates in preparation for DNA extraction. This isolate's DNA was characterized and analyzed through restriction digests. Once we obtained enough lysate we were able to send in the samples to be sequenced and further reviewed by bioinformatic analyses. DuncansLeg is a temperate phage that is a part of the L3 subcluster with 75,593 base pairs.

 

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