The effects of aerobic-resistance training and broccoli supplementation on plasma dectin-1 and insulin resistance in males with type 2 diabetes

Authors

• Ayoub Saeidi, University of Kurdistan
• Mohammad Soltani, Shahid Beheshti University
• Ali Daraei, University of British Columbia Okanagan
• Hanieh Nohbaradar, Alzahra University
• Marjan Mosalman Haghighi, Faculty of Medicine and Health
• Nikoo Khosravi, Alzahra University
• Kelly E. Johnson, Coastal Carolina University
• Ismail Laher, The University of British Columbia
• Anthony C. Hackney, Department of Nutrition
• Trisha A. Vandusseldorp, Kennesaw State University
• Hassane Zouhal, Université de Rennes

Document Type

Article

Publication Date

9-1-2021

Abstract

Background: This study aimed to evaluate the effects of a combination of aerobic-resistance training (CARET) and broccoli supplementation on dectin-1 levels and insulin resistance in men with type 2 diabetes mellitus (T2D). Methods: Forty-four males with T2D were randomly allocated to four groups (n = 11 each group): CARET + broccoli supplement (TS), CARET + placebo (TP), control + broccoli supplement (S), and control + placebo (CP). CARET was performed three days per week for 12 weeks. TS and S groups received 10 g of broccoli supplement per day for 12 weeks. All variables were assessed at baseline and 12 weeks. Results: Plasma dectin-1 levels were decreased in TS and TP groups compared with the CP group (p < 0.05). Cardiometabolic risk factors showed significant reductions in TP and TS groups compared to S and CP groups (p < 0.05). Conclusion: The combination of CARET and broccoli supplementation produced the largest improvements in insulin resistance and dectin-1 and other complications of T2D.

Comments

MDPI originally published this article.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Saeidi, A., Soltani, M., Daraei, A., Nohbaradar, H., Haghighi, M. M., Khosravi, N., Johnson, K. E., Laher, I., Hackney, A. C., VanDusseldorp, T. A., & Zouhal, H. (2021). The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes. Nutrients, 13(9), 3144. https://doi.org/10.3390/nu13093144. Available at https://digitalcommons.coastal.edu/kinesiology/