Presentation Title

pH Low Insertion Peptide (pHLIP) Insertion Pathway into the Membrane

Presentation Type

Presentation

Full Name of Faculty Mentor

Ganga Sharma, Physics and Engineering Science

Major

Biology

Presentation Abstract

The pH (low) insertion peptide (pHLIP) targets acidity at the surfaces of cancer cells and shows utility in a wide range of applications, including tumor imaging and intracellular delivery of therapeutic agents. It transforms from coil to interfacial helix and then inserts into the cell membrane with transmembrane orientation. Experimental, computational, and analytic studies have opened the door to develop a pHLIP technology platform for cancer diagnosis and treatment. This talk will mainly focus on our investigation in the quest to find optimal pHLIP insertion pathway into the membrane.

Location

Room 1

Start Date

21-4-2021 4:30 PM

End Date

21-4-2021 4:50 PM

Disciplines

Biology

This document is currently not available here.

Link to Room 1

">Virtual Session

Share

COinS
 
Apr 21st, 4:30 PM Apr 21st, 4:50 PM

pH Low Insertion Peptide (pHLIP) Insertion Pathway into the Membrane

Room 1

The pH (low) insertion peptide (pHLIP) targets acidity at the surfaces of cancer cells and shows utility in a wide range of applications, including tumor imaging and intracellular delivery of therapeutic agents. It transforms from coil to interfacial helix and then inserts into the cell membrane with transmembrane orientation. Experimental, computational, and analytic studies have opened the door to develop a pHLIP technology platform for cancer diagnosis and treatment. This talk will mainly focus on our investigation in the quest to find optimal pHLIP insertion pathway into the membrane.

https://digitalcommons.coastal.edu/ugrc/test1/test1track/24