Presentation Title

The influence of gut microbiota in development of Alzheimer's disease

Presentation Type

Presentation

Full Name of Faculty Mentor

Fang-Ju Lin, Biology

Major

Biology

Presentation Abstract

Alzheimer's disease is a neurodegenerative disease that effects the neurons in the brain and can lead to cognitive impairment and death. The main aspects of Alzheimer's research focus on genetic factors contributing to the disease, but the microbiota gut-brain-axis may be playing a potential role in Alzheimer's development. The human body has an abundant microbiota to help our bodies carry out daily needs, but the amount of microbiota present has to be keep in a tolerance range by the immune system. If there is an increase in the amount of gut microbiota present in the human body, inflammation can occur in the CNS and lead to a potential contributor to Alzheimer's development. The aim of this study is to survey the diversity of gut microbiota in the transgenic Alzheimer's fruit fly (Drosophila) model, in comparison with ones in the healthy wild-type Drosophila.

Location

Room 2

Start Date

22-4-2021 2:20 PM

End Date

22-4-2021 2:40 PM

Disciplines

Biology

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Apr 22nd, 2:20 PM Apr 22nd, 2:40 PM

The influence of gut microbiota in development of Alzheimer's disease

Room 2

Alzheimer's disease is a neurodegenerative disease that effects the neurons in the brain and can lead to cognitive impairment and death. The main aspects of Alzheimer's research focus on genetic factors contributing to the disease, but the microbiota gut-brain-axis may be playing a potential role in Alzheimer's development. The human body has an abundant microbiota to help our bodies carry out daily needs, but the amount of microbiota present has to be keep in a tolerance range by the immune system. If there is an increase in the amount of gut microbiota present in the human body, inflammation can occur in the CNS and lead to a potential contributor to Alzheimer's development. The aim of this study is to survey the diversity of gut microbiota in the transgenic Alzheimer's fruit fly (Drosophila) model, in comparison with ones in the healthy wild-type Drosophila.

https://digitalcommons.coastal.edu/ugrc/test1/test1track/16