Presentation Type

Poster

Full Name of Faculty Mentor

Megan Cevasco, Biology

Major

Biology

Presentation Abstract

The Human Immunodeficiency Virus (HIV) is globally distributed and effects millions of people worldwide. Better understanding the global distribution and diversity of the HIV virus allows for more accurate treatment, and tracing to be followed more closely. In this study, multiple sequence alignment tools were used to determine if there were group defining synapomorphies characterized by diversity in the gag gene. This was done by using seventeen sequenced HIV strains from six different countries, and generating a variety multiple sequences alignments under varied substitution and indel costs. Results showed that distinct genotypes of the HIV gag gene revealed both geographic and evolutionary patterns.

Location

Virtual Poster Session 1

Start Date

21-4-2021 12:00 PM

End Date

21-4-2021 2:00 PM

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Apr 21st, 12:00 PM Apr 21st, 2:00 PM

Synapomorphic Patterns in HIV Gag Gene Sequences

Virtual Poster Session 1

The Human Immunodeficiency Virus (HIV) is globally distributed and effects millions of people worldwide. Better understanding the global distribution and diversity of the HIV virus allows for more accurate treatment, and tracing to be followed more closely. In this study, multiple sequence alignment tools were used to determine if there were group defining synapomorphies characterized by diversity in the gag gene. This was done by using seventeen sequenced HIV strains from six different countries, and generating a variety multiple sequences alignments under varied substitution and indel costs. Results showed that distinct genotypes of the HIV gag gene revealed both geographic and evolutionary patterns.

 

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