Optimizing illuminating conditions of ROS in Caenorhabiditis elegans
Presentation Type
Event
Full Name of Faculty Mentor
Daniel Williams
Major
Biology
Presentation Abstract
Reactive oxygen species (ROS) are implicated in neurodegeneration that relates to several human health conditions such as Alzheimer's and Parkinson's disease. Caenorhabiditis elegans is a type of nematode that is used as a genetic model organism because of their well-established nervous system. Our lab uses a transgenic strain of C. elegans that expresses KillerRed in the GABA neuron. Illumination of these animals activates KillerRed and produces ROS, causing degeneration of GABA neurons and results in the loss of motor function. Our goal is to optimize illuminating conditions on populations of worms as a possible model of testing therapeutics.
Course
BIOL339
Location
Lib Jackson Student Union, Atrium
Start Date
17-4-2019 4:30 PM
End Date
17-4-2019 6:30 PM
Disciplines
Biology
Recommended Citation
Smith, Alysia, "Optimizing illuminating conditions of ROS in Caenorhabiditis elegans" (2019). Undergraduate Research Competition. 47.
https://digitalcommons.coastal.edu/ugrc/2019/poster/47
Optimizing illuminating conditions of ROS in Caenorhabiditis elegans
Lib Jackson Student Union, Atrium
Reactive oxygen species (ROS) are implicated in neurodegeneration that relates to several human health conditions such as Alzheimer's and Parkinson's disease. Caenorhabiditis elegans is a type of nematode that is used as a genetic model organism because of their well-established nervous system. Our lab uses a transgenic strain of C. elegans that expresses KillerRed in the GABA neuron. Illumination of these animals activates KillerRed and produces ROS, causing degeneration of GABA neurons and results in the loss of motor function. Our goal is to optimize illuminating conditions on populations of worms as a possible model of testing therapeutics.